This research explores the multifaceted role of Non-Governmental Organizations (NGOs) in promoting women’s empowerment globally. Drawing upon a comprehensive analysis of existing studies and literature, the review examines the diverse interventions and strategies employed by NGOs to address gender disparities and advance women’s rights. Key themes include advocacy and awareness-raising, capacity building, economic empowerment, health and reproductive rights, legal aid, education, political participation, community development, research, and partnerships. Through a systematic review methodology, the study synthesizes findings to provide insights into the effectiveness and significance of NGO initiatives in empowering women across different contexts. The review contributes to a deeper understanding of the complex dynamics shaping women’s empowerment efforts and highlights the pivotal role of NGOs in fostering gender equality and inclusive development.