Digital therapeutics (DTx) have emerged as a transformative innovation within the healthcare ecosystem, offering evidence-based therapeutic interventions delivered through software to prevent, manage, or treat diseases. Unlike conventional digital health tools, DTx are clinically validated and often regulated, ensuring their safety, efficacy, and integration into formal healthcare systems. The rapid expansion of digital therapeutics is driven by the increasing prevalence of chronic diseases, rising healthcare costs, and the growing demand for personalized and accessible care. Pharmacists, traditionally recognized for their role in medication dispensing and counseling, are increasingly assuming expanded responsibilities within digital healthcare frameworks. Their accessibility, clinical expertise, and frequent patient interactions position them as key facilitators in the implementation and optimization of digital therapeutics. This article explores the evolution, clinical applications, benefits, and challenges of DTx, while highlighting the expanding role of pharmacists in patient education, adherence monitoring, and interprofessional collaboration. The paper further examines regulatory considerations, integration into pharmacy practice, and future perspectives, emphasizing the need for training, policy support, and digital literacy. Ultimately, the integration of digital therapeutics into pharmacy practice has the potential to enhance patient outcomes, improve healthcare efficiency, and redefine the role of pharmacists in modern healthcare systems.