Blood metal analysis of plasmas from donors with and without SARS-CoV-2 using laser-induced breakdown spectroscopy and logistic regression
Author : Noureddine Melikechi, Helmar G. Adler, Ali Safi, Joshua E. Landis, Farhad Pourkamali-Anaraki, Kemal Efe Eseller, Kim Berlo, Danielle Bonito, Gregory R. Chiklis, and Weiming Xia Journa Name: BIOMEDICAL OPTICS EXPRESS Country : USA Volume: 15 issue: 1 Year: 2024 Views : 296Research on the correlation between metal levels in blood and Covid-19 infection has been conducted primarily by assessing how each individual blood metal is linked to different aspects of the disease using samples from donors with various levels of severity to Covid-19 infection. Using logistics regression on LIBS spectra of plasma samples collected pre- and post- Covid-19 pandemic from donors known to have developed various levels of antibodies to the SARS-Cov-2 virus, we show that relying on the levels of Na, K, and Mg together is more efficient at differentiating the two types of plasma samples than any single blood alone.
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