A business can be properly managed globally when it is under a supply chain. When it is a global supply chain, inflation has a huge effect on supply chain profit. Another important factor is the deterioration of products. Products can deteriorate during storage or transportation, which badly affects each supply chain player. This study develops a three-echelon supply chain model through which products can be delivered to customers easily. In this model, one producer and multiple buyers are considered, and each buyer has a separate group in which multiple suppliers have been taken. Inflation is also added to the model for inflationary fluctuations. To understand this model in real life, a numerical example is discussed and the total profit from the supply chain is extracted. Sensitivity analysis is also shown at the end of the model to find out the effect on the model due to changes in some parameters that affect this model highly. After developing this model, it was found that if the inflation rate falls, then the total profit will increase continuously. On the contrary, if the inflation rate increases, then, in this situation, the total profit will decrease continuously. At present, vaccine makers’ total profit can support the economy of any country, and in this model, the inflation rate decreases as profit increases.