Synthesis Characterization CNS and Analgesic Studies of methyl 4-[(1E)-3-(Cyclopropylamino)-2-(2-Fluorophenyl)-3-Oxoprop-1-en-1-yl]Benzoate

Asst. prof. Dr. P. Deivanayagam; Dean Dr. Selvaraj; Vice principal Rajarajan

Synthesis Characterization CNS and Analgesic Studies of methyl 4-[(1E)-3-(Cyclopropylamino)-2-(2-Fluorophenyl)-3-Oxoprop-1-en-1-yl]Benzoate

Author : Asst. prof. Dr. P. Deivanayagam, Dean Dr. Selvaraj, Vice principal Rajarajan Journa Name: INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH AND ENGINEERING TRENDS Country : India Volume: 9 issue: 6 Year: 2023 Views : 438

Abstract:

Organic synthesis is applicable in everyday life. Organic synthesis is very important in medicinal chemistry. A literature review of the medicinal chemistry approach is briefly carried out. In this article, 4-formylbenzoic acid is treated with thionyl chloride to form methanol-4-formylbenzoate. The product obtained is treated with 2-flurophenylacetic acid to give product 2. Product 2 is treated with cyclopropylamine to give the final product. The final product is treated with CNS and analgesic studies and the result is obtained.