×

Optical tomography in a single camera frame using fringe-encoded deep-learning full-field OCT

Author : Viacheslav Mazlin Journa Name: BIOMEDICAL OPTICS EXPRESS Country : USA Volume: 15 issue: 1 Year: 2024 Views : 346
Abstract:
Optical coherence tomography is a valuable tool for in vivo examination thanks to its superior combination of axial resolution, field-of-view and working distance. OCT images are reconstructed from several phases that are obtained by modulation/multiplexing of light wavelength or optical path. This paper shows that only one phase (and one camera frame) is sufficient for en face tomography. The idea is to encode a high-frequency fringe patterns into the selected layer of the sample using low-coherence interferometry. These patterns can then be efficiently extracted with a high-pass filter enhanced via deep learning networks to create the tomographic full-field OCT view. This brings 10-fold improvement in imaging speed, considerably reducing the phase errors and incoherent light artifacts related to in vivo movements. Moreover, this work opens a path for low-cost tomography with slow consumer cameras. Optically, the device resembles the conventional time-domain full-field OCT without incurring additional costs or a field-of-view/resolution reduction. The approach is validated by imaging in vivo cornea in human subjects. Open-source and easy-to-follow codes for data generation/training/inference with U-Net/Pix2Pix networks are provided to be used in a variety of image-to-image translation tasks.

Related Indexing Platform

Indexed

GS
Google Scholar
Search this title on Scholar
Search on Google Scholar
SS
Semantic Scholar
Search this title
Search on Semantic Scholar
Leave Your Comment

Related Reviewers