Measuring pulsatile cortical blood flow and volume during carotid endarterectomy
Author : Alexander I. Zavriyev, Kutlu Kaya, Kuan Cheng Wu, Eric T. Pierce, Maria Angela Franceschini, and Mitchell B. Robinson Journa Name: BIOMEDICAL OPTICS EXPRESS Country : USA Volume: 15 issue: 3 Year: 2024 Views : 434Carotid endarterectomy (CEA) involves removal of plaque in the carotid artery to reduce the risk of stroke and improve cerebral perfusion. This study aimed to investigate the utility of assessing pulsatile blood volume and flow during CEA. Using a combined near-infrared spectroscopy/diffuse correlation spectroscopy instrument, pulsatile hemodynamics were assessed in 12 patients undergoing CEA. Alterations to pulsatile amplitude, pulse transit time, and beat morphology were observed in measurements ipsilateral to the surgical side. The additional information provided through analysis of pulsatile hemodynamic signals has the potential to enable the discovery of non-invasive biomarkers related to cortical perfusion.
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