Abstract– Supply chain management performs by integrating procurement, suppliers, and facilities of manufacturers, distributors, retailers, and customers while they work together by the production, buying, and sales cycles. This supply chain needs active management since it is impacted by several aspects of the control of the business-like environmental conditions, fuel prices, and so on. While a company is more aware of these aspects, it can effectively manage them. With efficient management of supply chain, production, inventory, distribution, vendor, and sale records are in strict control. The SCM shows the management of expenses at each step and offers products to customers in a quick manner. The aim of this thesis is to explore the possibility of implementing Six Sigma in SCM of Indian SMEs. The Six Sigma application in SCM of SMEs is a new paradigm for improving quality which is practiced by many academics. This thesis is an attempt to provide road map application of Six Sigma in SMEs which are normally presumed to be in the section of large industries. This case study will help the Indian SMEs to carry out such projects which can lead them towards business improvement.