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Exploring in-vivo infrared spectroscopy for nail-based diabetes screening

Author : Daniela Lazaro-Pacheco, Philip F Taday, and Päivi Maria Paldánius Journa Name: BIOMEDICAL OPTICS EXPRESS Country : USA Volume: 15 issue: 3 Year: 2024 Views : 411
Abstract:
Diabetes screening is traditionally complex, inefficient, and reliant on invasive sampling. This study evaluates near-infrared spectroscopy for non-invasive detection of glycated keratin in nails in vivo. Glycation of keratin, prevalent in tissues like nails and skin, is a key indicator of T2DM risk. In this study involving 200 participants (100 with diabetes, 100 without), NIR’s efficacy was compared against a point-of-care HbA1c analyzer. Results showed a specificity of 92.9% in diabetes risk assessment. This study highlights the proposed NIR system potential as a simple, reliable tool for early diabetes screening and risk management in various healthcare settings.

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