Clarification on the understanding of contrast theory in relation to the article “ON and OFF receptive field processing in the presence of optical scattering”: comment

Jay Neitz and Maureen Neitz

Clarification on the understanding of contrast theory in relation to the article “ON and OFF receptive field processing in the presence of optical scattering”: comment

Author : Jay Neitz and Maureen Neitz Journa Name: BIOMEDICAL OPTICS EXPRESS Country : USA Volume: 15 issue: 2 Year: 2024 Views : 214

Abstract:

We are writing to address errors of misrepresentation in the article “ON and OFF receptive field processing in the presence of optical scattering” [Biomed. Opt. Express 14, 2618 (2023) [CrossRef] ]. In their investigation of predictions of “contrast theory” to explain the efficacy of diffusion optics technology (DOT), a myopia control lens design [Br. J. Ophthalmol. 107, 1709 (2023) [CrossRef] ], Breher et al. incorrectly indicated that our contrast theory proposed that the association between cone opsin gene splicing defects and myopia was due to differential involvement in ON- and OFF-visual pathways. In addition, the Authors write that we have “hypothesized enhanced ON contrast sensitivity in myopes,” but we predict the opposite.